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The MOSSAC trial stopped after analysis of the first 624 patients showed that the combination of MSC and G-CSF had no efficacy \[[@B36]\]. In a subsequent phase II clinical trial of MSC treatment of acute GvHD, Lindner and colleagues suggested that administration of MSC instead of G-CSF could reduce toxicity and give similar results \[[@B64]\]. The design of this trial also differed from the MOSSAC study in that the dose of MSC was directly correlated with the dose of G-CSF, and no control arm of G-CSF alone was used. This strategy probably made the trial more sensitive to a neutral effect of MSC. Nevertheless, another phase II trial was conducted in in vivo bone marrow allogeneic transplant patients to determine the safety and tolerability of the combined use of MSC and G-CSF \[[@B65]\]. The results of this trial were encouraging in that there was no evidence

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Video file format NCERT for Class 9 Physics: SChandPhysicsClass9pdf. is required to prove the statutory elements of his convictions beyond a reasonable doubt. Here, we hold that the evidence is sufficient to support the conviction. The jury was properly charged on the presumption of sanity. The jury had the opportunity to observe the manner of the defendant’s conduct. The jury was shown that defendant exhibited abnormal and bizarre actions such as cursing, making obscene statements and sexually exposing himself to the victim. Further, the jury was charged that some mental illness does not necessarily preclude criminal responsibility. The jury was instructed that if the defendant’s mental capacity was incapable of forming the requisite intent, “then the act would not constitute a crime.”
Defendant cites Bigham v. State, 261 La. 921, 261 So.2d 619 (1972), for the proposition that the evidence in this case was insufficient to sustain a conviction. In Bigham, the defendant had threatened his victim. Then, within fifteen minutes, while being escorted to an ambulance, the defendant suddenly attacked and kicked the victim “swinging and yelling like a wild man”. The defendant kicked the victim several more times as he lay on the ground. The court determined that these facts were insufficient to warrant a finding of specific intent to inflict injury as required by R.S. 14:14.
In the present case, defendant’s conduct was more bizarre than in Bigham. Further, defendant’s conduct was continuous. The jury could reasonably have determined that this continued conduct was not that of an average man in a similar situation. The jury could reasonably have determined that in a moment of insanity, defendant could act normally, but then for reasons other than insanity, return to a state of insanity without loss of the ability to form the requisite intent. The circumstances in this case were not one-time acts in which the defendant lost his identity. Rather, as in Bigham, the defendant here exhibited numerous bizarre actions as he advanced toward the victim. The defendant here exhibited sufficient symptoms of mental illness, especially delusions, which would have placed an ordinarily rational person on notice that his actions were irrational.
The jury had an opportunity to view the situation and the defendant. It is our view that there was sufficient evidence presented to
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